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In this way, he created tadpoles that were genetically identical to the one from which the intestinal cell was taken.This experiment showed that, despite previous failures, nuclei from somatic cells in a fully developed animal could be used for cloning.All previous cloning experiments used donor nuclei from cells in early embryos.In this experiment, the donor nuclei came from a slightly different source: cultured sheep cells, which were kept alive in the laboratory.
The lambs born from this procedure were named Megan and Morag.
Still, mammalian cloning was limited to using embryonic cells as nuclear donors.
Cloning using nuclei from differentiated adult somatic cells still wasn’t thought possible.
This experiment showed that mammalian embryos could be created by nuclear transfer.
To show that the embryos could continue developing, Bromhall would have had to place them into a mother rabbit's womb. Willadsen used a chemical process to separated one cell from an 8-cell lamb embryo.
Using a glass pipette as a tiny straw, Bromhall transferred the nucleus from a rabbit embryo cell into an enucleated rabbit egg cell.